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Degenerative Myelopathy in German Shepherds (Hind-Leg Weakness)

Degenerative myelopathy in German Shepherds: why older dogs lose hind-leg strength, the first signs to watch for, and how genetic testing helps.

2 min readUpdated 2026-09-28

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Is your older German Shepherd a little wobbly on its back legs? One possible cause is degenerative myelopathy (DM), a slow spinal cord disease, and this breed is one of the most often affected [1][2][4]. Here's what it is and when to see a vet.

What is degenerative myelopathy?

  • A slow breakdown of nerve fibres and their coating in the spinal cord [1].
  • It causes hind-leg weakness and loss of coordination that gets worse over time [2].
  • It usually starts around age eight or older [2].

Is it the same as hip dysplasia?

No. Both can change how an older dog walks, but they are different conditions [2]. Only a vet can tell them apart.

How does a dog get DM?

It's not an infection, and it doesn't spread between dogs. It's inherited and linked to a gene called SOD1 [1][2].

The twist: inheritance is "incomplete". A dog can carry two copies of the gene change and still never get sick [1][2].

Is there a genetic test?

Yes. A DNA test shows whether a dog carries zero, one or two copies of the SOD1 change [2][3]. Remember:

  • A result shows risk, not a diagnosis [1][2].
  • Testing breeding dogs is the main way to lower risk [2][3].
  • Getting a puppy? Ask if the parents were tested [2][3].

Did you know? One early clue can be on the floor, not the dog: scuffed or worn nails on the back feet, from toes dragging as it walks [2].

When should I see a vet?

See a licensed vet if your dog shows:

  • Slow-building weakness or wobbling in the back legs [2].
  • Back toenails that scuff or drag [2].
  • Growing trouble getting up or walking over several months [2].

DM is not an emergency like bloat. But new hind-leg weakness should always be checked, because other spine or joint problems, some treatable, can look similar at first [1][2].

FAQ

Why are my German Shepherd's back legs giving out?

There can be many reasons, including DM and other spine or joint problems [1][2]. A vet can tell which.

Does a positive genetic test mean my dog will get DM?

No. It shows risk only [1][2].

Can DM be cured or slowed?

This page doesn't cover treatment. Please talk to a licensed vet about your dog.

Sources (4)

The official and scientific references behind this article.

  1. Degenerative Diseases of the Spinal Column and Cord in Animals — Merck (MSD) Veterinary Manual, https://www.merckvetmanual.com/nervous-system/diseases-of-the-spinal-column-and-cord/degenerative-diseases-of-the-spinal-column-and-cord-in-animals (accessed 2026-09-28)
  2. Degenerative myelopathy — Cornell University College of Veterinary Medicine, Riney Canine Health Center, https://www.vet.cornell.edu/departments-centers-and-institutes/riney-canine-health-center/canine-health-topics/degenerative-myelopathy (accessed 2026-09-28)
  3. Degenerative Myelopathy (DM) — UC Davis School of Veterinary Medicine, Veterinary Genetics Laboratory, https://vgl.ucdavis.edu/test/degenerative-myelopathy (accessed 2026-09-28)
  4. Congenital and Inherited Spinal Cord Disorders in Dogs and Cats — Merck (MSD) Veterinary Manual, https://www.merckvetmanual.com/nervous-system/congenital-and-inherited-anomalies-of-the-nervous-system-in-small-animals/congenital-and-inherited-spinal-cord-disorders-in-dogs-and-cats (accessed 2026-09-28)

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